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020 _a9789811554711
_9978-981-15-5471-1
024 7 _a10.1007/978-981-15-5471-1
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
072 7 _aMJCL
_2thema
082 0 4 _a614.5999
_223
245 1 0 _aNovel therapeutic approaches for gastrointestinal malignancies
_h[electronic resource] /
_cedited by Ganji Purnachandra Nagaraju, Sujatha Peela.
250 _a1st ed. 2020.
264 1 _aSingapore :
_bSpringer Singapore :
_bImprint: Springer,
_c2020.
300 _aXII, 259 p. 53 illus., 39 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aDiagnostics and Therapeutic Advances in GI Malignancies,
_x2662-2696
505 0 _aChapter 1. Role of selected transcription factors in pancreatic and colorectal cancer growth and metastasis -- Chapter 2. Adiponectin in gastrointestinal malignancies -- Chapter 3. Small molecule-targeted therapies for GI cancers: success and failures -- Chapter 4. Epigenetic biomarkers for the detection of Gastrointestinal Cancers -- Chapter 5. CD151: A Lateral organizer and modulator of Tumor microenvironment in gastrointestinal cancers -- Chapter 6. Targeting Pathways in GI Malignancies -- Chapter 7. Identification of Potential Key Genes Involved In Progression of Gastric Cancer Using Bioinformatics Analysis -- Chapter 8. Recent Development in the biomarkers for the gastric cancer -- Chapter 9. Gastric Cancer and it's remedy -- Chapter 10. An intergenic variant rs4779584 between SCG5 and GREM1 contributes to the increased risk of colorectal cancer: A meta-analysis -- Chapter 11. Phytochemicals plus nanomaterial's on colorectal cancer -- Chapter 12. Pancreatic Ductal Adenocarcinoma and Type 2 Diabetes Mellitus: Distant Relatives or the Close Ones? -- Chapter 13. Tumor Biomarkers and Diagnosis of Pancreatic Adenocarcinoma -- Chapter 14. Immunotherapy in Gastrointestinal Malignancies -- Chapter 15. The Role of HIF-1α in Hepatocellular Carcinoma.
520 _aThis book provides an up-to-date overview of gastrointestinal malignancies, including prevention, early detection, intervention, and life-extending therapeutics. It also assesses various biomarkers used for diagnostics, prognostics and prediction of response to chemoresistance. Further, it discusses the latest trends in the use of small-molecule targeted therapies and immunotherapies as single agents or combination with other treatments. Since resistance to radiation and chemotherapy contribute to the high recurrence and poor survival rates, improving the outcome for GI malignancies is dependent on the introduction of new biomarkers and therapeutic agents. Lastly, the book systematically investigates novel theranostics approaches using nanotechnology for the detection, diagnosis, and personalized treatment of GI malignancies.
650 0 _aCancer research.
650 0 _aNanotechnology.
650 0 _aRadiology.
650 0 _aGene expression.
650 1 4 _aCancer Research.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B11001
650 2 4 _aNanotechnology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/Z14000
650 2 4 _aDiagnostic Radiology.
_0https://scigraph.springernature.com/ontologies/product-market-codes/H29013
650 2 4 _aGene Expression.
_0https://scigraph.springernature.com/ontologies/product-market-codes/B12010
700 1 _aNagaraju, Ganji Purnachandra.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aPeela, Sujatha.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
_z9789811554704
776 0 8 _iPrinted edition:
_z9789811554728
776 0 8 _iPrinted edition:
_z9789811554735
830 0 _aDiagnostics and Therapeutic Advances in GI Malignancies,
_x2662-2696
856 4 0 _uhttps://doi.org/10.1007/978-981-15-5471-1
912 _aZDB-2-SBL
912 _aZDB-2-SXB
950 _aBiomedical and Life Sciences (SpringerNature-11642)
950 _aBiomedical and Life Sciences (R0) (SpringerNature-43708)
999 _c551801
_d551736