000			06101cam a2200685Ii 4500
001			ocn933591214
003			OCoLC
005			20190719103156.0
006			m o d
007			cr |n|||||||||
008			160101t20162016enka ob 000 0 eng d
040			_aYDXCP _beng _erda _epn _cYDXCP _dN$T _dOCLCQ _dOPELS _dOCLCF _dCOO _dUSU _dMMU _dTMC _dOCLCO _dUIU _dOCLCO _dOCLCQ _dOCLCO _dOCLCQ _dZ5A _dCASUM _dOCLCO _dMERER _dOCLCQ _dOCLCO _dOCLCA _dU3W _dBUF _dOCLCO _dOCLCQ _dD6H _dNLE _dUKMGB _dOCLCO _dOCLCA
015			_aGBB6F4543 _2bnb
015			_aGBB6H8738 _2bnb
016	7		_a017799484 _2Uk
016	7		_a017691624 _2Uk
019			_a981886556
020			_a9780128020098 _q(electronic bk.)
020			_a0128020091 _q(electronic bk.)
020			_z9780128019177 _q(paperback)
020			_z0128019174 _q(paperback)
035			_a(OCoLC)933591214 _z(OCoLC)981886556
050		4	_aRC924.5.L85
060	0	0	_a2016 E-016
060	1	0	_aWD 380
072		7	_aHEA _x039000 _2bisacsh
072		7	_aMED _x014000 _2bisacsh
072		7	_aMED _x022000 _2bisacsh
072		7	_aMED _x112000 _2bisacsh
072		7	_aMED _x045000 _2bisacsh
082	0	4	_a616.7/72 _223
082	0	4	_a616.77 _222
245	0	0	_aSystemic lupus erythematosus : _bbasic, applied and clinical aspects / _cedited by George C. Tsokos.
264		1	_aLondon : _bAcademic Press is an imprint of Elsevier, _c[2016]
264		4	_c�2016
300			_a1 online resource (xxv, 600 pages) : _billustrations (chiefly color)
336			_atext _btxt _2rdacontent
336			_astill image _bsti _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
504			_aIncludes bibliographical references.
505	0		_aHistory of systemic lupus erythematosus -- The patient -- Epidemiology -- Measuring disease activity -- Disease development and outcomes -- Socioeconomic aspects of systemic lupus erythematosus -- Biomarkers in systemic lupus erythematosus -- Overview of the pathogenesis of systemic lupus erythematosus -- Systemic lupus erythematosus and the environment -- Genes and genetics in human systemic lupus erythematosus -- Hormones -- The complement system in systemic lupus erythematosus -- T cells -- Integrating current thinking on peripheral B-celltolerance in lupus -- Neutrophils in systemic lupus erythematosus -- The role of dendritic cells in systemic lupus erythematosus -- Cytokines -- Toll-like receptors, systemic lupus erythematosus -- The interferon system in lupus erythematosus -- Humoral pathogenesis : Fc[gamma] receptors in autoimmunity and end-organ damage -- Apoptosis, autophagy, and necrosis -- Infections in early systemic lupus erythematosus pathogenesis -- Origin of autoantibodies -- Anti-DNA antibodies -- Antihistone and antispliceosome antibodies -- Immune complexes in systemic lupus erythematosus -- Microrna in systemic lupus erythematosus -- Oxidative stress in systemic lupus erythematosus : causes, consequences, and treatment -- Reactive nitrogen intermediates in the pathogenesis of systemic lupus erythematosus -- Epigenetics -- What do mouse models teach us about human systemic lupus erythematosus? -- Genes and genetics of murine systemic lupus erythematosus -- Mechanisms of renal damage in systemic lupus erythematosus -- Mechanisms of vascular damage in systemic lupus erythematosus -- The mechanism of skin damage -- Pathogenesis of tissue injury in the brain in patients with systemic lupus erythematosus -- Constitutional symptoms and fatigue in systemic lupus erythematosus -- The musculoskeletal system in systemic lupus erythematosus -- Cutaneous lupus erythematosus -- The clinical evaluation of kidney disease in systemic lupus erythematosus -- The pathology of lupus nephritis -- Cardiovascular disease in systemic lupus erythematosus -- The lung in systemic lupus erythematosus -- Gastrointestinal, hepatic, and pancreatic disorders in systemic lupus erythematosus -- Systemic lupus erythematosus and infections -- Malignancies in systemic lupus erythematosus -- The nervous system in systemic lupus erythematosus -- Overlap syndromes -- Systemic lupus erythematosus and the eye -- Pregnancy and fertility in systemic lupus erythematosus -- Neonatal lupus : clinical spectrum, biomarkers, pathogenesis, and approach to treatment -- Incomplete lupus -- Childhood-onset systemic lupus erythematosus -- Drug-induced lupus -- Vasculitis in lupus -- Pathogenesis of antiphospholipid syndrome -- Antibodies and diagnostic tests in antiphospholipid syndrome -- Clinical manifestations -- Nonsteroidal anti-inflammatory drugs in systemic lupus erythematosus -- Value of antimalarial drugs in the treatment of lupus -- Systemic glucocorticoids -- Cytotoxic-immunosuppressive drug treatment -- Treatment of antiphospholipid syndrome -- New treatments for systemic lupus erythematosus -- Management lessons from clinical trials of kidney disease in systemic lupus erythematosus -- Repositioning drugs for systemic lupus erythematosus.
588	0		_aOnline resource; title from resource home page (ClinicalKey, viewed April 12, 2017).
650		0	_aSystemic lupus erythematosus.
650		7	_aHEALTH & FITNESS _xDiseases _xGeneral. _2bisacsh
650		7	_aMEDICAL _xClinical Medicine. _2bisacsh
650		7	_aMEDICAL _xDiseases. _2bisacsh
650		7	_aMEDICAL _xEvidence-Based Medicine. _2bisacsh
650		7	_aMEDICAL _xInternal Medicine. _2bisacsh
650		7	_aSystemic lupus erythematosus. _2fast _0(OCoLC)fst01141443
650	1	2	_aLupus Erythematosus, Systemic _xdiagnosis. _0(DNLM)D008180Q000175
650	2	2	_aLupus Erythematosus, Systemic _xphysiopathology. _0(DNLM)D008180Q000503
650	2	2	_aLupus Erythematosus, Systemic _xtherapy. _0(DNLM)D008180Q000628
650	2	2	_aBiomarkers. _0(DNLM)D015415
650	2	2	_aComorbidity. _0(DNLM)D015897
655		4	_aElectronic books.
700	1		_aTsokos, George C., _eeditor.
776	0	8	_iPrint version: _tSystemic lupus erythematosus. _dLondon : Elsevier/Academic Press, [2016] _z9780128019177 _w(OCoLC)926743093
856	4	0	_3ScienceDirect _uhttp://www.sciencedirect.com/science/book/9780128019177
999			_c503768 _d503703