TY  - BOOK
AU  - Decker,M.
TI  - Design of hybrid molecules for drug development
SN  - 9780081011188
AV  - RS420 
U1  - 615.19 23
PY  - 2017///
CY  - Oxford
PB  - Elsevier
KW  - Drugs
KW  - Design
KW  - MEDICAL
KW  - Pharmacology
KW  - bisacsh
KW  - fast
KW  - Drug Design
KW  - Electronic books
N1  - Includes bibliographical references and index
N2  - Design of Hybrid Molecules for Drug Development reviews the principles, advantages, and limitations involved with designing these groundbreaking compounds. Beginning with an introduction to hybrid molecule design and background as to their need, the book goes on to explore a range of important hybrids, with hybrids containing natural products, molecules containing NO- and H2S-donors, dual-acting compounds acting as receptor ligands and enzyme inhibitors, and the design of photoresponsive drugs all discussed. Drawing on practical case studies, the hybridization of molecules for development as treatments for a number of key diseases is then outlined, including the design of hybrids for Alzheimer's, cancer, and malaria. With its cutting-edge reviews of breaking developments in this exciting field, the book offers a novel approach for all those working in the design, development, and administration of drugs for a range of debilitating disorders
UR  - http://www.sciencedirect.com/science/book/9780081010112
ER  -