TY - BOOK AU - Tsokos,George C. TI - Systemic lupus erythematosus: basic, applied and clinical aspects SN - 9780128020098 AV - RC924.5.L85 U1 - 616.7/72 23 PY - 2016///] CY - London PB - Academic Press is an imprint of Elsevier KW - Systemic lupus erythematosus KW - HEALTH & FITNESS KW - Diseases KW - General KW - bisacsh KW - MEDICAL KW - Clinical Medicine KW - Evidence-Based Medicine KW - Internal Medicine KW - fast KW - Lupus Erythematosus, Systemic KW - diagnosis KW - physiopathology KW - therapy KW - Biomarkers KW - Comorbidity KW - Electronic books N1 - Includes bibliographical references; History of systemic lupus erythematosus -- The patient -- Epidemiology -- Measuring disease activity -- Disease development and outcomes -- Socioeconomic aspects of systemic lupus erythematosus -- Biomarkers in systemic lupus erythematosus -- Overview of the pathogenesis of systemic lupus erythematosus -- Systemic lupus erythematosus and the environment -- Genes and genetics in human systemic lupus erythematosus -- Hormones -- The complement system in systemic lupus erythematosus -- T cells -- Integrating current thinking on peripheral B-celltolerance in lupus -- Neutrophils in systemic lupus erythematosus -- The role of dendritic cells in systemic lupus erythematosus -- Cytokines -- Toll-like receptors, systemic lupus erythematosus -- The interferon system in lupus erythematosus -- Humoral pathogenesis : Fc[gamma] receptors in autoimmunity and end-organ damage -- Apoptosis, autophagy, and necrosis -- Infections in early systemic lupus erythematosus pathogenesis -- Origin of autoantibodies -- Anti-DNA antibodies -- Antihistone and antispliceosome antibodies -- Immune complexes in systemic lupus erythematosus -- Microrna in systemic lupus erythematosus -- Oxidative stress in systemic lupus erythematosus : causes, consequences, and treatment -- Reactive nitrogen intermediates in the pathogenesis of systemic lupus erythematosus -- Epigenetics -- What do mouse models teach us about human systemic lupus erythematosus? -- Genes and genetics of murine systemic lupus erythematosus -- Mechanisms of renal damage in systemic lupus erythematosus -- Mechanisms of vascular damage in systemic lupus erythematosus -- The mechanism of skin damage -- Pathogenesis of tissue injury in the brain in patients with systemic lupus erythematosus -- Constitutional symptoms and fatigue in systemic lupus erythematosus -- The musculoskeletal system in systemic lupus erythematosus -- Cutaneous lupus erythematosus -- The clinical evaluation of kidney disease in systemic lupus erythematosus -- The pathology of lupus nephritis -- Cardiovascular disease in systemic lupus erythematosus -- The lung in systemic lupus erythematosus -- Gastrointestinal, hepatic, and pancreatic disorders in systemic lupus erythematosus -- Systemic lupus erythematosus and infections -- Malignancies in systemic lupus erythematosus -- The nervous system in systemic lupus erythematosus -- Overlap syndromes -- Systemic lupus erythematosus and the eye -- Pregnancy and fertility in systemic lupus erythematosus -- Neonatal lupus : clinical spectrum, biomarkers, pathogenesis, and approach to treatment -- Incomplete lupus -- Childhood-onset systemic lupus erythematosus -- Drug-induced lupus -- Vasculitis in lupus -- Pathogenesis of antiphospholipid syndrome -- Antibodies and diagnostic tests in antiphospholipid syndrome -- Clinical manifestations -- Nonsteroidal anti-inflammatory drugs in systemic lupus erythematosus -- Value of antimalarial drugs in the treatment of lupus -- Systemic glucocorticoids -- Cytotoxic-immunosuppressive drug treatment -- Treatment of antiphospholipid syndrome -- New treatments for systemic lupus erythematosus -- Management lessons from clinical trials of kidney disease in systemic lupus erythematosus -- Repositioning drugs for systemic lupus erythematosus UR - http://www.sciencedirect.com/science/book/9780128019177 ER -