Liquid chromatography/time-of-flight mass spectrometry : principles, tools, and applications for accurate mass analysis / Imma Ferrer, E.M. Thurman.

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Includes bibliographical references and index.

Accurate mass measurements with orthogonal axis time-of-flight mass spectrometry / John C. Fjeldsted -- The mass defect, isotope clusters, and accurate mass for elemental determination / E. Michael Thurman, Imma Ferrer -- Ion compositions determined with increasing simplicity / Andrew H. Grange, G. Wayne Sovocool -- Existence and use of accurate mass databases and elemental composition tools for target and non-target analyses / Imma Ferrer, E. Michael Thurman -- Use of UPLC-(Q)TOF MS for rapid screening of organic micropollutants in water / Felix Hernández, Juan V. Sancho, Maria Ibáñez -- The use of accurate mass, isotope ratios, and MS/MS for the analysis of PPCPs in water / Michael C. Zumwalt -- Applications of LC/TOF-MS in the environmental field: when did it start and where is it going? / Imma Ferrer, E. Michael Thurman -- Liquid chromatography and ambient ionization time-of-flight mass spectrometry for the analysis of genuine and counterfeit pharmaceuticals / Facundo M. Fernández [and others] -- Quantitative analysis of veterinary drug residues by sub 2-(mu)m particulate high-performance liquid chromatography columns and time-of-flight mass spectrometry (UPLC-TOF) / Anton Kaufmann -- Industrial applications of liquid chromatography time-of-flight mass spectrometry / Jeffrey R. Gilbert [and others] -- Comprehensive toxicological and forensic drug screening by LC/TOF-MS / Ilkka Ojanpera, Anna Pelander, Suvi Ojanperä -- Application of UPLC/TOF-MS for residue analysis of veterinary drugs and growth-promoting agents in products of animal origin / Alida (Linda) A.M. Stolker -- Accurate mass measurements with a reflectron time-of-flight mass spectrometer and the direct analysis in real time (DART) interface for the identification of unknown compounds below masses of 500 DA / O. David Sparkman, Patrick R. Jones, Matthew Curtis -- Comparison of LC/TOF-MS and LC/MS-MS for the analysis of 100 pesticides in food: finding the "crossover point" / E. Michael Thurman [and others].

Time of flight mass spectrometry identifies the elements of a compound by subjecting a sample of ions to a strong electrical field. Illuminating emerging analytical techniques in high-resolution mass spectrometry, Liquid Chromatography Time-of-Flight Mass Spectrometry shows readers how to analyze unknown and emerging contaminants & mdash;such as antibiotics, steroids, analgesics & mdash;using advanced mass spectrometry techniques. The text combines theoretical discussion with concrete examples, making it suitable for analytical chemists, environmental chemists, organic chemists, medicinal chemists.