Wellcome

The natural anti-gal antibody as foe turned friend in medicine / Uri Galili, PhD.

By: Galili, Uri [author.]Material type: TextTextPublisher: London, United Kingdom : Academic Press, an imprint of Elsevier, [2018]Copyright date: �2018Description: 1 online resource (xviii, 300 pages) : illustrationsContent type: text Media type: computer Carrier type: online resourceISBN: 9780128133637; 0128133635; 9780128133620; 0128133627Subject(s): Antigens | Antigen-antibody reactions | SCIENCE -- Life Sciences -- Microbiology | Antigen-antibody reactions | Antigens | Antigens | Antigen-Antibody ReactionsGenre/Form: Electronic books. | Electronic book.Additional physical formats: Print version:: Natural anti-gal antibody as foe turned friend in medicine.DDC classification: 616.0792 LOC classification: QR187.A1NLM classification: QW 573Online resources: ScienceDirect
Contents:
Anti-gal in humans and its antigen the ?-gal epitope -- Why do we produce anti-gal -- Anti-gal comprises most of anti-blood group b antibodies -- Anti-gal interaction with Trypansoma, Leishmania, and Plasmodium parasites -- Anti-gal b cells are tolerized by a ?-gal epitopes in the absence of t cell help -- Anti-gal and other immune barriers in xenotransplantation -- Anti-gal IgE mediates allergies to red meat -- Anti-gal and autoimmunity -- Anti-gal-mediated amplification of viral vaccine efficacy -- Cancer immunotherapy by anti-gal-mediated in situ conversion of tumors into autologous vaccines -- Anti-gal as cancer cell destroying antibody and as antibiotics targeted by ?-gal bifunctional molecules -- Acceleration of wound and burn healing by anti-gal/?-gal nanoparticles interaction -- Anti-gal and anti-non gal antibodies in regeneration of extracellular matrix bio-implants -- Post infarction regeneration of ischemic myocardium by intramyocardial injection of ?-gal nanoparticles -- Regeneration of injured spinal cord and peripheral nerves by ?-gal nanoparticles -- Inhalation of ?-gal/sialic acid liposomes for decreasing influenza virus infection.
Summary: The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the?-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book.
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Item type Current library Call number Status Date due Barcode
Ebooks Ebooks Mysore University Main Library
Not for loan EBKELV1109

Includes bibliographical references and index.

Specialized.

Print version record.

Online resource; title from PDF title page (EBSCO, viewed September 25, 2017).

The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the?-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book.

Anti-gal in humans and its antigen the ?-gal epitope -- Why do we produce anti-gal -- Anti-gal comprises most of anti-blood group b antibodies -- Anti-gal interaction with Trypansoma, Leishmania, and Plasmodium parasites -- Anti-gal b cells are tolerized by a ?-gal epitopes in the absence of t cell help -- Anti-gal and other immune barriers in xenotransplantation -- Anti-gal IgE mediates allergies to red meat -- Anti-gal and autoimmunity -- Anti-gal-mediated amplification of viral vaccine efficacy -- Cancer immunotherapy by anti-gal-mediated in situ conversion of tumors into autologous vaccines -- Anti-gal as cancer cell destroying antibody and as antibiotics targeted by ?-gal bifunctional molecules -- Acceleration of wound and burn healing by anti-gal/?-gal nanoparticles interaction -- Anti-gal and anti-non gal antibodies in regeneration of extracellular matrix bio-implants -- Post infarction regeneration of ischemic myocardium by intramyocardial injection of ?-gal nanoparticles -- Regeneration of injured spinal cord and peripheral nerves by ?-gal nanoparticles -- Inhalation of ?-gal/sialic acid liposomes for decreasing influenza virus infection.

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