Functionalized Nanomaterials for the Management of Microbial Infection : a Strategy to Address Microbial Drug Resistance / edited by Rabah Boukherroub, Sabine Szunerits, Djamel Drider.

Front Cover; Functionalized Nanomaterials for the Management of Microbial Infection; Copyright Page; Contents; List of Contributors; Preface; 1 Resistance to Antibiotics and Antimicrobial Peptides: A Need of Novel Technology to Tackle This Phenomenon; 1.1 Resistance to Antibiotics; 1.2 Resistance to Bacteriocins Produced by Gram-Positive Bacteria (GPB); 1.3 Conclusion and Prospects; Acknowledgments; References; 2 The Role of the Food Chain in the Spread of Antimicrobial Resistance (AMR); 2.1 Introduction; 2.2 AMR in Foodborne Pathogenic Bacteria; 2.3 AMR in Food-Related Beneficial Microbes.

2.4 Routes of Transmission of AMR Throughout the Food Chain2.4.1 Foods of Animal Origin; 2.4.2 Foods of Nonanimal Origin; 2.4.3 Primary Production and Food Processing Environments and Food Processing Technologies; 2.4.3.1 Role of Biocides in AMR Acquisition and Spread; 2.4.3.2 Food Processing Technologies and AMR; 2.5 Conclusions; References; 3 Penetrating the Bacterial Biofilm: Challenges for Antimicrobial Treatment; 3.1 Introduction; 3.1.1 Antimicrobial Treatment: In Desperate Need of a Wind of Change; 3.1.2 The Biofilm Lifestyle.

3.2 How Biofilms Pose a Challenge to the Diffusion of Antibiotics3.2.1 Mass Transport Phenomena in Biofilms; 3.2.2 Dense Cell Clusters; 3.2.3 Binding Interactions Between Antibiotics and Matrix Constituents; 3.2.3.1 Physicochemical Binding to Matrix Polymers; 3.2.3.2 Inactivation of Antibiotics by Enzymes Present in the Biofilm Matrix; 3.3 How to Improve Antibiotic Delivery to Biofilm Cells?; 3.3.1 Interference With the Biofilm Structure; 3.3.2 Nanocarriers for Improved Delivery of Antibiotics in Biofilms; 3.3.2.1 Nanocarriers Protect Antibiotics From Interactions With Biofilm Components.

3.3.2.2 Nanocarriers can be Designed to Increase Local Antibiotic Delivery3.3.2.3 Nanocarriers Can Shuttle Antibiotics Inside Bacterial Cells; 3.3.2.4 Responsive Nanoparticles: Antibiotic Release on Demand; 3.4 Conclusion; References; 4 Metal Nanoparticles for Microbial Infection; 4.1 Introduction; 4.2 Silver Nanoparticles for Microbial Infection; 4.2.1 Silver Nanoparticles Against Bacterial Infection; 4.2.2 Silver Nanoparticles Against Fungal Infection; 4.2.3 Silver Nanoparticles Against Viral Infection; 4.2.4 Silver Nanoparticles Against Protozoal Infection.

4.2.5 Medical Applications of Silver Nanoparticles4.3 Copper Nanoparticles for Microbial Infection; 4.3.1 Copper Nanoparticles Against Bacterial Infection; 4.3.2 Copper Nanoparticles Against Fungal Infection; 4.3.3 Medical Applications of Copper Nanoparticles; 4.4 Gold Nanoparticles for Microbial Infection; 4.4.1 Gold Nanoparticles for Therapeutic Intervention; 4.4.2 Gold Nanoparticles for Antimicrobial Drug Delivery; 4.4.3 Gold Nanoparticles for Photodynamic Therapy; 4.4.4 Gold Nanoparticles for Photothermal Treatment; 4.4.5 Gold Nanoparticles for Diagnostic Applications.

Includes bibliographical references and index.