MARC details
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05986cam a2200709Ii 4500 |
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ocn941779213 |
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20190719103215.0 |
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m o d |
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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160229t20162016ne ob 001 0 eng d |
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eng |
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101682941 |
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945612137 |
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958095726 |
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1066467360 |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9780128019740 |
Qualifying information |
(electronic bk.) |
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International Standard Book Number |
0128019743 |
Qualifying information |
(electronic bk.) |
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International Standard Book Number |
0128019689 |
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International Standard Book Number |
9780128019689 |
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9780128019689 |
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(OCoLC)941779213 |
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(OCoLC)945612137 |
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(OCoLC)958095726 |
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(OCoLC)1066467360 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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RC108 |
060 #4 - |
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QW 541 |
072 #7 - |
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HEA |
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039000 |
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bisacsh |
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MED |
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014000 |
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MED |
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022000 |
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MED |
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112000 |
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MED |
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045000 |
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082 04 - |
Classification number |
616/.044 |
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23 |
245 04 - TITLE STATEMENT |
Title |
The innate immune response to non-infectious stressors : |
Remainder of title |
human and animal models / |
Statement of responsibility, etc |
edited by Massimo Amadori. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
1 online resource |
505 0# - |
Formatted contents note |
Cover; Title Page; Copyright Page; Dedication; Contents; Contributors; Preface; References; Chapter 1 -- An Overview of the Innate Immune Response to Infectious and Noninfectious Stressors; Introduction; Recognition; PRRs and PAMPs; Toll-Like Receptors; Signaling; C-Type Lectin Receptors; Signaling; The RIG-I-Like Receptors; Signaling; NLRs and the Inflammasome; Signaling; AIM2-Like Receptors; Signaling; C-GAS and Other DNA Sensors; Signaling; RAGE; Soluble PRRs; PRR localization; DAMPs; Nucleic Acids; ATP; Uric Acid; Heat-Shock Proteins; Mitochondrial Danger Signals; HMGB1; DAMP; Chaperone. |
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Formatted contents note |
Secondary Danger SignalChemokine; Redox State; Degradation Products of the Extracellular Matrix; Secondary endogenous danger signals; Emerging and Homeostatic Danger Signals; Conclusions; References; Chapter 2 -- Homeostatic Inflammation as Environmental-Adaptation Strategy; Introduction; Innate immune sensors recognize various endogenous ligands including metabolites; Modulation of metabolites recognized by extracellular sensors; Modification of nucleic acid-sensing receptors; DNA and RNA are modified to be recognized or not by innate immune sensors. |
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Formatted contents note |
Priming effect of noninfectious inflammation on immune responseCorrelation with inflammatory and autoimmune diseases in adipose tissue; Excessive activation of nucleic acid-sensing sensors induces autoimmune diseases; Regulation of homeostatic inflammation and innate immune sensors for controlling immune system and homeostasis; References; Chapter 3 -- The Molecular Basis of the Immune Response to Stressed Cells and Tissues; Innate immune responses: receptors and ligands; Stress-mediated regulation of immune receptors and ligands: an overview. |
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Formatted contents note |
Transcriptional Regulation of NK-Cell Activating Ligands Modulated by Stress ResponsesPosttranscriptional Regulation of Stress-Controlled NK-Cell Activating Ligands; Translational and Posttranslational Regulation of Stress-Modulated NK-Cell Activating Ligands; Different forms of stress regulate innate immunity; Osmotic Stress; Thermal Stress; Genotoxic Stress; Oxidative Stress; Endoplasmic Reticulum Stress; Stress-Induced Senescence; Immunogenic cell death: putting all the things together; References; Chapter 4 -- Modulation of Innate Immunity by Hypoxia; Hypoxia; Hypoxia sensing. |
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Formatted contents note |
Hypoxia-Inducible FactorsNuclear Factor kB; Hypoxia effects on leukocytes; Myeloid Cells; Monocytes/Macrophages; Granulocytes; Dendritic Cells; Lymphoid Cells; Hypoxia, myeloid cells, and diseases; Pulmonary Hypertension (PH); Rheumatoid Arthritis; Inflammatory Bowel Disease; Atherosclerosis; Ischemia; Preeclampsia; Allergy; Cancer; Therapeutic targeting of hypoxic signaling; HIF Activators; HIF Inhibitors; Acknowledgments; References; Chapter 5 -- Metabolic Stress, Heat Shock Proteins, and Innate Immune Response; Introduction; Metabolic stress conditions; Metabolic stress and innate immunity. |
650 #0 - |
Topical term or geographic name as entry element |
Chronic diseases. |
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Topical term or geographic name as entry element |
Immune response. |
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Topical term or geographic name as entry element |
HEALTH & FITNESS |
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Topical term or geographic name as entry element |
MEDICAL |
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Topical term or geographic name as entry element |
MEDICAL |
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Topical term or geographic name as entry element |
MEDICAL |
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Topical term or geographic name as entry element |
MEDICAL |
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Topical term or geographic name as entry element |
Chronic diseases. |
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Topical term or geographic name as entry element |
Immune response. |
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Topical term or geographic name as entry element |
Chronic Disease. |
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Topical term or geographic name as entry element |
Immunity, Innate. |
700 1# - |
Personal name |
Amadori, Massimo, |
Relator term |
editor. |
856 40 - |
Uniform Resource Identifier |
http://www.sciencedirect.com/science/book/9780128019689 |
264 #1 - |
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Amsterdam : |
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Academic Press is an imprint of Elsevier, |
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[2016] |
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�2016 |
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text |
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txt |
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rdacontent |
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computer |
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online resource |
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Includes bibliographical references and index. |
588 0# - |
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Online resource; title from PDF title page (EBSCO, viewed March 17, 2016). |
520 ## - |
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The Innate Immune Response to Non-infectious Stressors: Human and Animal Models highlights fundamental mechanisms of stress response and important findings on how the immune system is affected, and in turn affects such a response. In addition, this book covers the crucial link between stress response and energy metabolism, prompts a re-appraisal of some crucial issues, and helps to define research priorities in this fascinating, somehow elusive field of investigation. |
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General. |
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Clinical Medicine. |
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Diseases. |
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Evidence-Based Medicine. |
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Internal Medicine. |
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bisacsh |
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fast |
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(OCoLC)fst00860072 |
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fast |
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(OCoLC)fst00967867 |
655 #0 - |
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Electronic book. |
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Electronic books. |
776 08 - |
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Print version: |
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Innate immune response to non-infectious stressors : human and animal models. |
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Amsterdam, [Netherlands] : Academic Press, �2016 |
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xxvii, 247 pages |
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9780128019689 |
856 40 - |
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ScienceDirect |
880 #4 - |
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264-00 |
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�2016 |