Wellcome

Regenerative Medicine and Stem Cell Biology

Regenerative Medicine and Stem Cell Biology [electronic resource] / edited by Nagwa El-Badri. - 1st ed. 2020. - X, 374 p. 45 illus., 16 illus. in color. online resource. - Learning Materials in Biosciences, 2509-6133 . - Learning Materials in Biosciences, .

Chapter 1. Basic Concepts of Stem Cells: The Facts and Hype in Stem Cells Research and Development -- Chapter 2. Embryonic and Pluripotent Stem Cells -- Chapter 3. Adult Stem Cells: Hematopoietic Stem Cells, and Control Of Hematopoiesis -- Chapter 4. Adult Stem Cells: Adult Stem Cells: Mesenchymal Stromal Cells, Endothelial Progenitor Cells and Pericytes -- Chapter 5. Cancer Stem Cells and the Development of Cancer -- Chapter 6. Stem Cell Applications In Metabolic Disorders: Diabetes Mellitus -- Chapter 7. Epigenetics in Stem Cell Biology -- Chapter 8. Practicum: Isolation of Bone Marrow and Adipose Tissue Mesenchyme Stromal Cells -- Chapter 9. Induced Pluripotent Stem Cells: Biology, History and in-vitro Generation -- Chapter 10. Tissue Engineering Modalities and Nanotechnology -- Chapter 11. Practicum: Scaffold engineering using the amniotic membrane -- Chapter 12. The Scientific Method, Ethical Consideration and Implications in Stem Cell Research.

This textbook covers the basic aspects of stem cell research and applications in regenerative medicine. Each chapter includes a didactic component and a practical section. The book offers readers insights into: How to identify the basic concepts of stem cell biology and the molecular regulation of pluripotency and stem cell development. How to produce induced pluripotent stem cells (iPSCs) and the basics of transfection. The biology of adult stem cells, with particular emphasis on mesenchymal stromal cells and hematopoietic stem cells, and the basic mechanisms that regulate them. How cancer stem cells arise and metastasize, and their properties. How to develop the skills needed to isolate, differentiate and characterize adult stem The clinical significance of stem cell research and the potential problems that need to be overcome. Evaluating the use of stem cells for tissue engineering and therapies (the amniotic membrane) The applications of bio-nanotechnology in stem cell research. How epigenetic mechanisms, including various DNA modifications and histone dynamics, are involved in regulating the potentiality and differentiation of stem cells. The scientific methods, ethical considerations and implications of stem cell research.

9783030553593

10.1007/978-3-030-55359-3 doi


Biomedical engineering.
Regenerative medicine.
Tissue engineering.
Reproductive medicine.
Stem cells.
Cancer research.
Biomedical Engineering/Biotechnology.
Regenerative Medicine/Tissue Engineering.
Reproductive Medicine.
Stem Cells.
Cancer Research.
Biomedical Engineering and Bioengineering.

R856-R857

610.28

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