Wellcome

Design and analysis of quality of life studies in clinical trials

Fairclough, Diane Lynn.

Design and analysis of quality of life studies in clinical trials [electronic resource] / Diane L. Fairclough. - 2nd ed. - Boca Raton : CRC Press, c2010. - xx, 404 p. : ill. - Chapman & Hall/CRC interdisciplinary statistics series . - Interdisciplinary statistics. .

"A Chapman & Hall book."

Includes bibliographical references and index.

Introduction and examples -- Study design and protocol development -- Models for longitudinal studies I -- Models for longitudinal studies II -- Moderation and mediation -- Characterization of missing data -- Analysis of studies with missing data -- Simple imputation -- Multiple imputation -- Pattern mixture and other mixture models -- Random effects dependent dropout -- Selection models -- Multiple endpoints -- Composite endpoints and summary measures -- Quality adjusted life-years (QALYs) and Q-TWiST -- Analysis plans and reporting results.




Mode of access: World Wide Web.

9781420061185 (ebook : PDF)


Clinical trials--Longitudinal studies.
Clinical trials--Statistical methods.
Quality of life--Research--Methodology.


Electronic books.

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